IDO-IN-1
IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 59 nM.
Product Specifications
CAS Number
914638-30-5
UNSPSC
12352005
Hazard Statement
H228, H315, H319
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/IDO-IN-1.html
Purity
98.14
Solubility
DMSO : 120 mg/mL (ultrasonic)
Smiles
NC1=NON=C1/C(NO)=N/C2=CC(Br)=C(F)C=C2
Molecular Formula
C9H7BrFN5O2
Molecular Weight
316.09
Precautions
H228, H315, H319
References & Citations
[1]Yue EW, et al. Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model. J Med Chem. 2009 Dec 10;52 (23) :7364-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO
Available Sizes
Frequently Asked Questions
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