IDO-IN-1
IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 59 nM.
Product Specifications
CAS Number
[914638-30-5]
UNSPSC
12352005
Hazard Statement
H228, H315, H319
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/IDO-IN-1.html
Purity
98.14
Solubility
DMSO : 120 mg/mL (ultrasonic)
Smiles
NC1=NON=C1/C(NO)=N/C2=CC(Br)=C(F)C=C2
Molecular Formula
C9H7BrFN5O2
Molecular Weight
316.09
Precautions
H228, H315, H319
References & Citations
[1]Yue EW, et al. Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model. J Med Chem. 2009 Dec 10;52 (23) :7364-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
12031019 1 PC
7000g Empty Flash Column Set, with stainless steel end caps, clamps, plastic column tube, filter frits, O-rings, column adapter (for 1/4", 1/8", 3/16" LC lines, with male and female connectors), 1set/pk
Ask
View Details 
038926-ML490 100 µL
NF kappa B, phosphorylated (S536) (RELA, NFKB3, Transcription factor p65, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B Cells 3) (MaxLight 490) discontinued
Ask
View Details