Norisoboldine (Standard)

Norisoboldine (Standard) is the analytical standard of Norisoboldine. This product is intended for research and analytical applications. Norisoboldine is an orally active natural aryl hydrocarbon receptor (AhR) agonist. Norisoboldine, as a major isoquinoline alkaloid present in Radix Linderae, can be used for the research of Rheumatoid arthritis and Ulcerative colitis[1][2].

Product Specifications

CAS Number

[23599-69-1]

Product Name Alternative

(+) -Laurelliptine (Standard)

UNSPSC

12352005

Target

Adenosine Receptor; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/norisoboldine-standard.html

Smiles

OC1=C(OC)C=C2CCN[C@@]3([H])CC4=CC(O)=C(OC)C=C4C1=C23

Molecular Formula

C18H19NO4

Molecular Weight

313.35

References & Citations

[1]Luo Y, et al. Therapeutic effect of norisoboldine, an alkaloid isolated from Radix Linderae, on collagen-induced arthritis in mice. Phytomedicine. 2010;17 (10) :726-731.|[2]Lv Q, et al. Norisoboldine, a natural AhR agonist, promotes Treg differentiation and attenuates colitis via targeting glycolysis and subsequent NAD+/SIRT1/SUV39H1/H3K9me3 signaling pathway. Cell Death Dis. 2018;9 (3) :258. Published 2018 Feb 15.