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Raspberry ketone glucoside

Raspberry ketone glucoside is a melanogenesis inhibitor. Raspberry ketone glucoside inhibits melanogenesis by activating the IL6/JAK1/STAT3 pathway, inhibiting the transcriptional activity of MITFa, and its downstream expression levels of the TYR and TYRP1a genes. Raspberry ketone glucoside shows remarkable whitening activity on both B16F10 cells in vitro and zebrafish model in vivo[1].

Product Specifications

CAS Number

[38963-94-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Interleukin Related; JAK; STAT

Type

Natural Products

Related Pathways

Epigenetics; Immunology/Inflammation; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/raspberry-ketone-glucoside.html

Concentration

10mM

Purity

99.52

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

CC(CCC(C=C1)=CC=C1O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO)=O

Molecular Formula

C16H22O7

Molecular Weight

326.34

Precautions

H302, H315, H319, H335

References & Citations

[1]Guo QQ, et al. Raspberry ketone glucoside suppresses melanin synthesis through IL6/JAK1/STAT3 signal pathway. Eur Rev Med Pharmacol Sci. 2023 May;27 (9) :4254-4268.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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