VH032 analogue-2
VH032 analogue-2 is a VH032 (HY-120217) analog that acts as a ligand for VHL, recruiting von Hippel-Lindau (VHL) protein. VH032 analogue-2 will remove the protective group under acidic conditions, and can be directly used for the synthesis of PROTAC molecules. VH032 analogue-2 is a key intermediate for the synthesis of PROTACs based on VHL ligands.
Product Specifications
CAS Number
[1448189-66-9]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vh032-analogue-2.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)C)NC(OC(C)(C)C)=O)=O)C[C@H](O)C3
Molecular Formula
C26H36N4O5S
Molecular Weight
516.65
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![[4-[(4,6-Dichloro-1,3,5-triazin-2-yl)amino]phenyl]arsonic Acid (>90%)](https://cdn.genprice.uk/products/572/1606648334469/imageurl/trc-d434035-50mg.webp)
[4-[(4,6-Dichloro-1,3,5-triazin-2-yl)amino]phenyl]arsonic Acid (>90%)
