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SEC61B Rabbit pAb

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008]

Product Name Alternative

Protein transport protein Sec61 subunit beta

UniProt

P60468

Swiss Prot

P60468

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human SEC61B AA range: 30-110

Target

SEC61B

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; ELISA

Concentration

1 mg/ml

Dilution

IHC-p 1:50-200, ELISA (peptide) 1:5000-20000

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Endoplasmic reticulum membrane ; Single-pass membrane protein .

Other Product Names

Protein transport protein Sec61 subunit beta

Gene ID (Human)

10952

Available Sizes

Curated Selection

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