Plasma kallikrein/KLKB1, Human (HEK293, His)

Plasma kallikrein (KLKB1) serves as an enzyme, cleaving Lys-Arg and Arg-Ser bonds to release bradykinin from HMW kininogen. It plays a crucial role in the reciprocal activation of factor XII, especially upon binding to a negatively charged surface. Besides its role in the kinin system, KLKB1 may contribute to the renin-angiotensin system by converting prorenin into renin. Plasma kallikrein/KLKB1 Protein, Human (HEK293, His) is the recombinant human-derived Plasma kallikrein/KLKB1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Plasma kallikrein/KLKB1 Protein, Human (HEK293, His) is 619 a.a., with molecular weight of 72-80 kDa.

GCLTQLYENA FFRGGDVASM YTPNAQYCQM RCTFHPRCLL FSFLPASSIN DMEKRFGCFL KDSVTGTLPK VHRTGAVSGH SLKQCGHQIS ACHRDIYKGV DMRGVNFNVS KVSSVEECQK RCTNNIRCQF FSYATQTFHK AEYRNNCLLK YSPGGTPTAI KVLSNVESGF SLKPCALSEI GCHMNIFQHL AFSDVDVARV LTPDAFVCRT ICTYHPNCLF FTFYTNVWKI ESQRNVCLLK TSESGTPSSS TPQENTISGY SLLTCKRTLP EPCHSKIYPG VDFGGEELNV TFVKGVNVCQ ETCTKMIRCQ FFTYSLLPED CKEEKCKCFL RLSMDGSPTR IAYGTQGSSG YSLRLCNTGD NSVCTTKTST RIVGGTNSSW GEWPWQVSLQ VKLTAQRHLC GGSLIGHQWV LTAAHCFDGL PLQDVWRIYS GILNLSDITK DTPFSQIKEI IIHQNYKVSE GNHDIALIKL QAPLNYTEFQ KPICLPSKGD TSTIYTNCWV TGWGFSKEKG EIQNILQKVN IPLVTNEECQ KRYQDYKITQ RMVCAGYKEG GKDACKGDSG GPLVCKHNGM WRLVGITSWG EGCARREQPG VYTKVAEYMD WILEKTQSSD GKAQMQSPA