GA32
Product Specifications
UNSPSC Description
GA32 (compound 58r) is potent androgen receptor (AR)/glucocorticoid receptor (GR) dual inhibitor with IC50 values of 0.13 μM and 0.83 μM for AR and GR, respectively. GA32 inhibits the proliferation of Enzalutamide (HY-70002) resistance castration-resistant prostate cancer both in vitro and in vivo[1].
Target Antigen
Androgen Receptor; Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ga32.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CC1=CC=C(NC(C2=CC=CC(S(=O)(N3C4=C(CCC3)C=CC=C4)=O)=C2)=O)C=C1
Molecular Weight
417.48
References & Citations
[1]Li C, et al. Design and Synthesis of Dual-Target Inhibitors Targeting Androgen Receptors and Glucocorticoid Receptors to Overcome Antiandrogen Resistance in Castration-Resistant Prostate Cancer. J Med Chem. 2024 Feb 22.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163340/GA32-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163340/GA32-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1386811-71-7
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
