PRMT5:MEP50 PPI
PRMT5:MEP50 PPI is a novel PRMT5:MEP50 protein-protein interaction (PRMT5:MEP50 PPI) inhibitor, shows anti-tumor activity and anti-proliferative activity of lung and prostate cancer cells[1].
Product Specifications
CAS Number
3031536-71-4
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/prmt5-mep50-ppi.html
Concentration
10mM
Purity
98.09
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
CCC1=NOC(C)=C1COC2=CC(C(NNC(C3=NC4=C(C=C3)C=CC=C4)=O)=O)=CC=C2
Molecular Formula
C24H22N4O4
Molecular Weight
430.46
References & Citations
[1]Asberry AM, et al. Discovery and Biological Characterization of PRMT5:MEP50 Protein-Protein Interaction Inhibitors. J Med Chem. 2022 Oct 7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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