Human BIP Protein

<strong>Human BIP Protein </strong>_x000D_ <strong>Catalog number:</strong> B2011608_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> glucose-regulated protein 78kD protein, HSPA5 protein, heat shock 70kDa protein 5 protein, Binding immunoglobulin protein , MIF2, GRP78 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Ibrahim IM, Abdelmalek DH, Elfiky AA. GRP78: A cell's response to stress Life Sci. 2019 Jun 1;226:156-163._x000D_ 2: Wang J, Lee J, Liem D, Ping P. HSPA5 Gene encoding Hsp70 chaperone BiP in the endoplasmic reticulum Gene. 2017 Jun 30;618:14-23._x000D_ 3: Kopp MC, Larburu N, Durairaj V, Adams CJ, Ali MMU. UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor Nat Struct Mol Biol. 2019 Nov;26(11):1053-1062._x000D_ 4: Bandla S, Diaz S, Nasheuer HP, FitzGerald U. ATPase activity of human binding immunoglobulin protein (BiP) variants is enhanced by signal sequence and physiological concentrations of Mn(2) FEBS Open Bio. 2019 Aug;9(8):1355-1369._x000D_ 5: Pobre KFR, Poet GJ, Hendershot LM. The endoplasmic reticulum (ER) chaperone BiP is a master regulator of ER functions: Getting by with a little help from ERdj friends J Biol Chem. 2019 Feb 8;294(6):2098-2108._x000D_ 6: Kabakov AE, Gabai VL. HSP70s in Breast Cancer: Promoters of Tumorigenesis and Potential Targets/Tools for Therapy Cells. 2021 Dec 7;10(12):3446._x000D_ 7: Kania E, Pająk B, Orzechowski A. Calcium homeostasis and ER stress in control of autophagy in cancer cells Biomed Res Int. 2015;2015:352794._x000D_ 8: Meyer BA, Doroudgar S. ER Stress-Induced Secretion of Proteins and Their Extracellular Functions in the Heart Cells. 2020 Sep 10;9(9):2066._x000D_ 9: Kabakov A, Yakimova A, Matchuk O. Molecular Chaperones in Cancer Stem Cells: Determinants of Stemness and Potential Targets for Antitumor Therapy Cells. 2020 Apr 6;9(4):892._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/30194633">10: Yang L, Guan G, Lei L, Lv Q, Liu S, Zhan X, Jiang Z, Gu X. Palmitic acid induces human osteoblast-like Saos-2 cell apoptosis via endoplasmic reticulum stress and autophagy Cell Stress Chaperones. 2018 Nov;23(6):1283-1294. </a>_x000D_ _x000D_ <strong>Products Related to Human BIP Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>