Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Pyridoxal phosphate

Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia.

Product Specifications

CAS Number

54-47-7

Product Name Alternative

Pyridoxal 5′-phosphate; Pyridoxyl phosphate

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Amyloid-β; Endogenous Metabolite; ERK; Reverse Transcriptase

Type

Natural Products

Related Pathways

Anti-infection; MAPK/ERK Pathway; Metabolic Enzyme/Protease; Neuronal Signaling; Stem Cell/Wnt

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer; Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Pyridoxal_phosphate.html

Purity

99.95

Solubility

DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 5 mg/mL (ultrasonic)

Smiles

O=CC1=C(O)C(C)=NC=C1COP(O)(O)=O

Molecular Formula

C8H10NO6P

Molecular Weight

247.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Modak MJ. Pyridoxal 5' phosphate: a selective inhibitor of oncornaviral DNA polymerases. Biochem Biophys Res Commun. 1976 Jul 12;71 (1) :180-7.|[2]Grin IR, et al. Inactivation of NEIL2 DNA glycosylase by pyridoxal phosphate reveals a loop important for substrate binding. Biochem Biophys Res Commun. 2010 Mar 26;394 (1) :100-5.|[3]Zhang P, et al., High concentrations of pyridoxal stimulate the expression of IGFBP1 in HepG2 cells through upregulation of the ERK/c‑Jun pathway. Mol Med Rep. 2013 Oct;8 (4) :973-8.|[4]Choi JM, et al., Membrane-Free Stem Cells and Pyridoxal 5'-Phosphate Synergistically Enhance Cognitive Function in Alzheimer's Disease Mouse Model. Antioxidants (Basel) . 2022 Mar 21;11 (3) :601.|[5]Zhang L, et al., Pyridoxine 5'-phosphate oxidase is a novel therapeutic target and regulated by the TGF-β signalling pathway in epithelial ovarian cancer. Cell Death Dis. 2017 Dec 13;8 (12) :3214.|[6]Nakamura S, et al., Pyridoxal phosphate prevents progression of diabetic nephropathy. Nephrol Dial Transplant. 2007 Aug;22 (8) :2165-74.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

Launched

Isoform

Human Endogenous Metabolite

Citation 01

J Agric Food Chem. 2025 Oct 15;73 (41) :25991-25997.|Int J Biol Macromol. 2025 Jul 21;320 (Pt 4) :146219.|Nat Immunol. 2023 Jan;24 (1) :162-173.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

ASK1 (MAP3K5) Rabbit Polyclonal Antibody
TA378270 100 µL

ASK1 (MAP3K5) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Auto Chemistry Analyzer BANA-805
BANA-805 1 Unit

Auto Chemistry Analyzer BANA-805

Sign In for Pricing
View Details
TBC1D2B (NM_144572) Human Over-expression Lysate
LC430114 20 µg

TBC1D2B (NM_144572) Human Over-expression Lysate

Sign In for Pricing
View Details
Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF640R conjugate, 0.1mg/mL
BNC400252-500 1x 500 µL

Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) (AE-1), CF640R conjugate, 0.1mg/mL

Sign In for Pricing
View Details
ZDHHC7 (NM_001145548) Human Over-expression Lysate
LC428939 20 µg

ZDHHC7 (NM_001145548) Human Over-expression Lysate

Sign In for Pricing
View Details
Arhgap31 Mouse Gene Knockout Kit (CRISPR)
KN501506 1 Kit

Arhgap31 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details