KTX-582 intermediate-2
Product Specifications
UNSPSC Description
KTX-582 intermediate-2 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].
Target Antigen
Apoptosis
Type
ADC Related
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/ktx-582-intermediate-2.html
Purity
96.18
Solubility
10 mM in DMSO
Smiles
O=C(N1C2C(NC(CC2)=O)=O)C3=CC=CC(N[C@H]4C[C@@H](C4)OCCCNC)=C3C1=O.Br
Molecular Weight
495.37
References & Citations
[1]Mainolfi, et al. Preparation of heterocycles as IRAK degraders and uses thereof. World Intellectual Property Organization, WO2022147465 A1. 2022-07-07.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-49432/KTX-582-intermediate-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-49432/
Clinical Information
No Development Reported
CAS Number
2434850-07-2
Available Sizes
Curated Selection
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