Oligomycin C

Oligomycin C is a macrolide antibiotic produced by Streptomyces strains. Oligomycin C exhibits a strong activity against Aspergillus niger, Alternaria alternata, Botrytis cinerea and Phytophthora capsici but no activity toward bacteria[1].

Product Specifications

CAS Number

[11052-72-5]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Antibiotic; Fungal

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/oligomycin-c.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H]([C@H]([C@@H](C([C@H]([C@H]([C@@H](C/C=C/C=C/[C@@]([H])(CC[C@]1([C@H]([C@@]([H])(O2)[C@@H]([C@]3(O1)CC[C@@H]([C@@]([H])(O3)C[C@@H](C)O)C)C)C)[H])CC)C)O)C)=O)C)O)C)[C@H]([C@@H]([C@H](/C=C/C2=O)C)O)C

Molecular Formula

C45H74O10

Molecular Weight

775.06

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Yang PW, et al. Oligomycins A and C, major secondary metabolites isolated from the newly isolated strain Streptomyces diastaticus. Folia Microbiol (Praha) . 2010;55 (1) :10-16.|[2]Han S, et al. Functional characterization of CYP107W1 from Streptomyces avermitilis and biosynthesis of macrolide oligomycin A. Arch Biochem Biophys. 2015;575:1-7.