Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

C-Reactive Protein (CRP) (174-185)

C-Reactive Protein (CRP) is an anti-pneumococcal plasma protein that can serve as an inflammatory marker. C-Reactive protein can protect mice from pneumococcal infection by activating complement. C-Reactive protein can inhibit the activation of caspase-3/9 through the CD64/AKT/mTOR pathway, thereby promoting chemotherapy resistance in mice with tongue squamous cell carcinoma[1][5].

Product Specifications

CAS Number

147516-85-6

UNSPSC

12352209

Target

Akt; Caspase; mTOR

Type

Peptides

Related Pathways

Apoptosis; PI3K/Akt/mTOR

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/c-reactive-protein-crp-174-185.html

Purity

99.88

Solubility

H2O : 10 mg/mL (ultrasonic)

Smiles

CC(C)C[C@@H](C(O)=O)NC([C@H](C(C)C)NC([C@H](CC(N)=O)NC([C@H]1N(C([C@H](CO)NC([C@H](CC2=CC=CC=C2)NC([C@H]3N(C(CNC(CNC([C@H](CC(C)C)NC([C@H](CC4=CC=C(O)C=C4)NC([C@H]([C@@H](C)CC)N)=O)=O)=O)=O)=O)CCC3)=O)=O)=O)CCC1)=O)=O)=O

Molecular Formula

C62H93N13O16

Molecular Weight

1276.48

References & Citations

[1]Singh SK, et al. Complement Activation by C-Reactive Protein Is Critical for Protection of Mice Against Pneumococcal Infection. Front Immunol. 2020 Aug 13;11:1812. |[2]Devaraj S, et al. C-reactive protein stimulates superoxide anion release and tissue factor activity in vivo. Atherosclerosis. 2009 Mar;203 (1) :67-74. |[3]Chen JY, et al. C-reactive protein derived from perivascular adipose tissue accelerates injury-induced neointimal hyperplasia. J Transl Med. 2020 Feb 11;18 (1) :68. |[4]Tang Y, et al. C-reactive protein promotes acute kidney injury by impairing G1/S-dependent tubular epithelium cell regeneration. Clin Sci (Lond) . 2014 May;126 (9) :645-59. |[5]Yan X, et al. C-reactive protein promotes tongue squamous cell carcinoma chemoresistance by inhibiting the activation of caspase-3/9 via the CD64/AKT/mTOR pathway. Hum Cell. 2021 Sep;34 (5) :1424-1433. |[6]Ansar W, et al. C-reactive protein and the biology of disease. Immunol Res. 2013 May;56 (1) :131-42.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

MTX1 Human Gene Knockout Kit (CRISPR)
KN400800 1 Kit

MTX1 Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Ifnb1 Mouse Gene Knockout Kit (CRISPR)
KN308140BN 1 Kit

Ifnb1 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Albumin (BCP) Microplate Assay Kit
RDSM140 100 Assays

Albumin (BCP) Microplate Assay Kit

Sign In for Pricing
View Details
Ɑ-Biotinamido-ω-Squaric Acid Ester Amido PEG
1320000-25-50.1G 1 g

Ɑ-Biotinamido-ω-Squaric Acid Ester Amido PEG

Sign In for Pricing
View Details
STEAP1 (NM_012449) Human Recombinant Protein
TP303970M 100 µg

STEAP1 (NM_012449) Human Recombinant Protein

Sign In for Pricing
View Details
D-Glucitol-13C6
TRC-G415802-5MG 5 mg

D-Glucitol-13C6

Sign In for Pricing
View Details