Human BDNF / Abrineurin Protein (E. coli), premium grade

Brain-derived neurotrophic factor (BDNF) along with nerve growth factor (NGF), neurotrophin-3 (NT-3), and neurotrophin-4/5 (NT-4/5) are members of the neurotrophin family of trophic factors. The neurotrophins play essential roles in the development, survival, and function of a wide range of neurons in both the peripheral and central nervous systems. The neurotrophins interact with two cell surface receptors, the low affinity P75 receptor and the Trk family of high affinity tyrosine kinase receptors. NGF preferentially binds TrkA, BDNF and NT4/5 bind TrkB, and NT-3 binds TrkC (and TrkA to a lesser extent) .

Product Specifications

Background

Specifications

This protein carries no "tag". The protein has a calculated MW of 13.6 kDa. The protein migrates as 15 kDa±3 kDa under reducing (R) condition, and 13 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE)

Accession Number

P23560-1

Expression Region

His 129 - Arg 247

Host

E. coli

Target

BDNF

Conjugation

Unconjugated

Tag

Native

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.