Glucocorticoid receptor agonist-1 Ala-Ala-Mal
Product Specifications
UNSPSC Description
Glucocorticoid receptor agonist-1 Ala-Ala-Mal (compound 88) is a glucocorticosteroid, and an agonist of glucocorticoid receptor. Glucocorticoid receptor agonist-1 Ala-Ala-Mal can be conjugated with Adalimumab (HY-P9908) to prepare an ADC[1].
Target Antigen
Drug-Linker Conjugates for ADC; Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related;Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/glucocorticoid-receptor-agonist-1-ala-ala-mal.html
Smiles
O=C([C@]([C@@]1([H])C[C@@]2([H])[C@@](CCC3=CC4=O)([H])[C@]([C@]3(C=C4)C)([H])[C@H]5O)(O[C@@](C(C=C6)=CC=C6CC7=CC(NC([C@H](C)NC([C@H](C)NC(CCN(C8=O)C(C=C8)=O)=O)=O)=O)=CC=C7)([H])O1)[C@]2(C5)C)CO
Molecular Weight
862.96
References & Citations
[1]McPherson, et al. Preparation of glucocorticoid receptor agonist and immunoconjugates thereof: World Intellectual Property Organization, WO2017210471[P]. 2017-12-07.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-137882/Glucocorticoid-receptor-agonist-1-Ala-Ala-Mal-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-137882/Glucocorticoid-receptor-agonist-1-Ala-Ala-Mal-SDS-MedChemExpress.pdf
CAS Number
2166376-51-6
Available Sizes
Curated Selection
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