Bac7 (1-35)
Bac7 (1-35) is a proline-rich antimicrobial peptide. Bac7 (1-35) efficiently binds to different regions of prokaryote ribosomes, leading to the inhibition of protein synthesis. Bac7 (1-35) demonstrates in vitro activity against P. aeruginosa strains[1].
Product Specifications
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bac7-1-35.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N3[C@@H](CCC3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N4[C@@H](CCC4)C(N[C@@H](CCCNC(N)=N)C(N5[C@@H](CCC5)C(N[C@@H](CCCNC(N)=N)C(N6[C@@H](CCC6)C(N[C@@H](CCCNC(N)=N)C(N7[C@@H](CCC7)C(N[C@@H](CC(C)C)C(N8[C@@H](CCC8)C(N[C@@H](CC9=CC=CC=C9)C(N%10[C@@H](CCC%10)C(N[C@@H](CCCNC(N)=N)C(N%11[C@@H](CCC%11)C(NCC(N%12[C@@H](CCC%12)C(N[C@@H](CCCNC(N)=N)C(N%13[C@@H](CCC%13)C(N[C@@H]([C@@H](C)CC)C(N%14[C@@H](CCC%14)C(N[C@@H](CCCNC(N)=N)C(N%15[C@@H](CCC%15)C(N[C@@H](CC(C)C)C(N%16[C@@H](CCC%16)C(N[C@@H](CC%17=CC=CC=C%17)C(N%18[C@@H](CCC%18)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N
Molecular Formula
C196H322N68O36
Molecular Weight
4207.09
References & Citations
[1]Runti G, et al. The Mechanism of Killing by the Proline-Rich Peptide Bac7 (1-35) against Clinical Strains of Pseudomonas aeruginosa Differs from That against Other Gram-Negative Bacteria. Antimicrob Agents Chemother. 2017 Mar 24;61 (4) :e01660-16.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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