Anti-Hu TCR Valpha24-Jalpha18 Purified

*Montoya CJ, Pollard D, Martinson J, Kumari K, Wasserfall C, Mulder CB, Rugeles MT, Atkinson MA, Landay AL, Wilson SB: Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11. Immunology. 2007 Sep;122 (1) :1-14., URL: https://pubmed.ncbi.nlm.nih.gov/17662044/, *Vyth-Dreese FA, Sein J, van de Kasteele W, Dellemijn TA, van den Bogaard C, Nooijen WJ, de Gast GC, Haanen JB, Bex A: Lack of anti-tumour reactivity despite enhanced numbers of circulating natural killer T cells in two patients with metastatic renal cell carcinoma. Clin Exp Immunol. 2010 Dec;162 (3) :447-59., URL: https://pubmed.ncbi.nlm.nih.gov/20942806/, *Krovi SH, Gapin L: Invariant natural killer T cell subsets - more than just developmental intermediates. Front Immunol. 2018 Jun 20;9:1393., URL: https://pubmed.ncbi.nlm.nih.gov/29973936/, *Chamoto K, Guo T, Scally SW, Kagoya Y, Anczurowski M, Wang CH, Rahman MA, Saso K, Butler MO, Chiu PP, Julien JP, Hirano N: Key residues at third CDR3β position impact structure and antigen recognition of human invariant NK TCRs. J Immunol. 2017 Feb 1;198 (3) :1056-1065. , URL: https://pubmed.ncbi.nlm.nih.gov/28003379/

The mouse monoclonal antibody 6B11 recognizes an extracellular epitope within V alpha 24 J alpha 18 TCR, which is expressed by invariant NK T cells (iNKT) .