Pm26TGF-β1 peptide (TFA)

Pm26TGF-β1 TFA peptide is a peptide that mimics a portion of the human TGF-β1 molecule. pm26TGF-β1 peptide TFA shows high affinity for the TGF-β1 receptor. pm26TGF-β1 peptide TFA displays potent anti-inflammatory properties and does not exhibit neutrophils’ chemoattraction[1][2].

Product Specifications

UNSPSC

12352209

Target

TGF-β Receptor

Type

Peptides

Related Pathways

TGF-beta/Smad

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pm26tgf-β1-peptide-tfa.html

Purity

99.68

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(O)C(F)(F)F.O=C(N[C@@H](CS)C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CS)C(NCC(NCC(NCC(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Molecular Formula

C56H94F3N19O22S2

Molecular Weight

1506.58

References & Citations

[1]Emília R Vaz, et al. A Short Peptide That Mimics the Binding Domain of TGF-β1 Presents Potent Anti-Inflammatory Activity. PLoS One. 2015 Aug 27;10 (8) :e0136116.|[2]Rodrigues, Tamiris Sabrina. Evaluation of the action of the synthetic peptide pm26TGF-β1, human TGF-β1 mimetic, on TNF-α induced apoptosis in Drosophila melanogaster. Universidade Federal de Uberlândia, 2017.