2'-Deoxycytidine-2'-13C
2'-Deoxycytidine-2'-13C is 13C labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu) . 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer[1][2][3].
Product Specifications
Product Name Alternative
Deoxycytidine-13C; Cytosine deoxyriboside-13C; Deoxyribose cytidine-13C
UNSPSC
12352005
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-deoxycytidine-2-13c.html
Smiles
O[C@H]1[13CH2][C@H](N2C=CC(N)=NC2=O)O[C@@H]1CO
Molecular Formula
C8 13CH13N3O4
Molecular Weight
228.21
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Iwazaki A, et al. Intravenously administered 2'-deoxycytidine suppresses mouse myeloma tumor growth. Biol Pharm Bull. 2012;35 (2) :251-5.|[3]Horn D, et al. Inhibition of biological effects of bromodeoxyuridine by deoxycytidine: correlation with decreased incorporation of bromodeoxyuridine into DNA. Somatic Cell Genet. 1976 Sep;2 (5) :469-81.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
Phase 3
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