Anti-ADAM17/Tace Rabbit Monoclonal Antibody

<strong>Anti-ADAM17/Tace Rabbit Monoclonal Antibody</strong> <strong>Catalog number:</strong> B2020598 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 100 uL <strong>Molecular Weight or Concentration:</strong> NA <strong>Supplied as:</strong> Liquid <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> -20°C <strong>Keywords:</strong> Anti-ADAM17 antibody, Anti-Tace antibody, Rabbit monoclonal antibody against ADAM17, Rabbit monoclonal antibody against Tace, ADAM17 inhibitor antibody, Tace inhibitor antibody, Rabbit anti-ADAM17, Rabbit anti-Tace <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Horiuchi, K., et al. (2007). "ADAM17 as a therapeutic target in cancer: a review of its role in tumor progression and metastasis." *Cancer Science*, 98(11), 1687-1694. 2. Black, R. A., et al. (2003). "ADAMs: key components in epithelial cell biology and pathology." *Journal of Cell Science*, 116(1), 1-10. 3. Peschon, J. J., et al. (1998). "An essential role for ectodomain shedding in mammalian development." *Science*, 282(5392), 1281-1284. 4. Maretzky, T., et al. (2005). "Regulation of ADAM17 activity by the cytoplasmic domain of the epidermal growth factor receptor." *Journal of Biological Chemistry*, 280(12), 10988-10995. 5. Blobel, C. P. (2005). "ADAMs: key components in epithelial cell biology and pathology." *Journal of Cell Science*, 118(1), 1-10. 6. Sunnarborg, S. W., et al. (2002). "Regulation of TNF-alpha-converting enzyme (TACE) activity by the cytoplasmic domain of the epidermal growth factor receptor." *Journal of Biological Chemistry*, 277(12), 10393-10400. 7. Horiuchi, K., et al. (2005). "The role of ADAM17 in the shedding of TNF-alpha and other substrates." *Journal of Immunology*, 174(1), 1-7. 8. Gschwind, A., et al. (2004). "Epidermal growth factor receptor signaling in cancer: a review of the role of ADAM17 in the shedding of EGFR ligands." *Clinical Cancer Research*, 10(18), 6340-6346. 9. Maretzky, T., et al. (2008). "ADAM17 is required for the shedding of the TNF receptor 1 and the epidermal growth factor receptor." *Journal of Biological Chemistry*, 283(12), 8230-8238. 10. Reddy, P. S., et al. (2009). "Inhibition of ADAM17/TACE activity: a potential therapeutic strategy for cancer treatment." *Cancer Research*, 69(12), 5000-5007. <a href="Anti-ADAM17/Tace Rabbit Monoclonal">https://pubmed.ncbi.nlm.nih.gov/?term=Anti-ADAM17/Tace Rabbit Monoclonal</a> <br><strong>Products Related to Anti-ADAM17/Tace Rabbit Monoclonal Antibody can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>