NAP1051
NAP1051 is a biomimetic analog of lipin A4 that achieves anti-tumor effects by targeting the inflammatory tumor microenvironment. NAP1051 inhibits neutrophil chemotaxis to fMLP and stimulates macrophage efferocytosis by activating AKT. NAP1051 can be used in colorectal cancer research[1].
Product Specifications
CAS Number
864516-77-8
UNSPSC
12352211
Target
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nap1051.html
Smiles
COC(CCC[C@H](O)[C@H](O)/C=C/C1=CC=CC(/C=C/[C@H](O)CCCCC)=C1)=O
Molecular Formula
C23H34O5
Molecular Weight
390.51
References & Citations
[1]Tiange Dong, et al. "NAP1051, a lipoxin A4 biomimetic analogue, demonstrates antitumor activity against the tumor microenvironment." Molecular Cancer Therapeutics 20.12 (2021) : 2384-2397.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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