Big endothelin-1 (rat 1-39)
Big endothelin-1 (rat 1-39) is a 39-residues peptide. Big endothelin-1 (rat 1-39) induces diuretic and natriuretic response in conscious Sprague-Dawley rats. Big endothelin-1 (rat 1-39) raises blood pressure in mice[1].
Product Specifications
CAS Number
135842-15-8
UNSPSC
12352209
Target
Endothelin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/big-endothelin-1-rat-1-39.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(CO)C(NC(CSSCC(C(NC(C(C)C)C(NC(CC1=CC=C(C=C1)O)C(NC2CC3=CC=CC=C3)=O)=O)=O)NC4=O)C(NC(CO)C(NC(CO)C(NC(CC(C)C)C(NC(CCSC)C(NC(CC(O)=O)C(NC(CCCCN)C(NC4CCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(CSSCC(C(NC(CC5=CNC=N5)C(NC(CC(C)C)C(NC(CC(O)=O)C(NC(C(C)CC)C(NC(C(C)CC)C(NC(CC6=CNC7=CC=CC=C67)C(NC(C(C)C)C(NC(CC(N)=O)C(NC(C(O)C)C(N8C(CCC8)C(NC(CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(NC(C(C)C)C(N[C@@H](C(C)C)C(N9C(CCC9)C(NC(CC%10=CC=C(C=C%10)O)C(NCC(N[C@H](CC(C)C)C(NCC(N[C@H](CO)C(N%11C(CCC%11)C(NC(CO)C(NC(CCCNC(N)=N)C(NC(CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC2=O)N
Molecular Formula
C192H292N50O58S5
Molecular Weight
4389.00
References & Citations
[1]Hoffman A, et al. Opposite effects of endothelin-1 and Big-endothelin- (1-39) on renal function in rats. Eur J Pharmacol. 1990 Jul 17;182 (3) :603-6.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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