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PF9601N

PF9601N, an monoamine oxidase B (MAO-B) inhibitor, possesses neuroprotective properties in several in vitro and in vivo models of Parkinson's disease (PD) . PF9601N can be used for the research of neurodegenerative diseases mediated by excitotoxicity[1]. PF9601N is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[133845-63-3]

UNSPSC

12352005

Hazard Statement

H319

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/pf9601n.html

Purity

99.85

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

C#CCNCC(N1)=CC2=C1C=CC(OCC3=CC=CC=C3)=C2

Molecular Formula

C19H18N2O

Molecular Weight

290.36

Precautions

P264-P280-P305+P351+P338

References & Citations

[1]Irene Bolea, et al. Neuroprotective effects of the MAO-B inhibitor, PF9601N, in an in vivo model of excitotoxicity. CNS Neurosci Ther. 2014 Jul;20 (7) :641-50.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Curated Selection

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