Hemsleyadin D

Hemsleyadin D is a triterpenoid compound derived from Hemsleya penxianensis with antitumor activity. Its IC50 values against K562, MGC-803, U118, HepG2, A549, and MCF-7 cells are 93.9, 47.1, 25.9, 56.1, 66.3, and 67.6 μM, respectively[1].

Product Specifications

CAS Number

[586960-44-3]

UNSPSC

12352211

Target

Others

Type

Natural Products

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hemsleyadin-d.html

Smiles

CC(OC(C)(C)CCC([C@](O)([C@]1([H])[C@@]2([C@@](C[C@H]1OC(C)=O)([C@@]3([H])[C@@](C(C2)=O)([C@@]4([H])C(C(C)([C@@H]([C@H](C4)O)O)C)=CC3)C)C)C)C)=O)=O

Molecular Formula

C34H52O9

Molecular Weight

604.77

References & Citations

[1]Li Z, et al. Cucurbitane triterpenoid entities derived from Hemsleya penxianensis triggered glioma cell apoptosis via ER stress and MAPK signalling cross-talk. Bioorg Chem. 2022 Oct;127:106013.