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TANDEM

TANDEM (Des-N-tetramethyltriostin A) is a synthetic antibiotic drug that has the activity of inhibiting the growth of tumor cells. TANDEM can be used in combination with chemotherapy to enhance the inhibitory effect. TANDEM has shown significant inhibitory effects on a variety of cancer cell lines in in vitro experiments. The structure of TANDEM allows it to effectively target tumor cells during the inhibition process. TANDEM's mechanism of action involves interfering with cell proliferation and survival pathways[1].

Product Specifications

CAS Number

63478-55-7

Product Name Alternative

Des-N-tetramethyltriostin A

UNSPSC

12352209

Target

Antibiotic

Type

Peptides

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tandem.html

Smiles

O=C([C@H](C(C)C)NC([C@H]1NC([C@H](C)N2)=O)=O)OC[C@@H](NC(C3=NC(C=CC=C4)=C4N=C3)=O)C(N[C@@H](C)C(N[C@@H](CSSC1)C(N[C@@H](C(C)C)C(OC[C@@H](NC(C5=NC(C=CC=C6)=C6N=C5)=O)C2=O)=O)=O)=O)=O

Molecular Formula

C46H54N12O12S2

Molecular Weight

1031.12

References & Citations

[1]The short-term safety and efficacy of TANDEM microspheres of various sizes and doxorubicin loading concentrations for hepatocellular carcinoma treatment

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

Phase 4

Frequently Asked Questions

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