Thalidomide-NH-C4-amide-C3-Br
Thalidomide-NH-C4-amide-C3-Br is a conjugate of the E3 ligase ligand Thalidomide with a linker and can be used in the synthesis of PROTAC TBL1X degrader-1.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thalidomide-nh-c4-amide-c3-br.html
Smiles
BrCCCNC(CCCCNC1=C(C(N(C2C(NC(CC2)=O)=O)C3=O)=O)C3=CC=C1)=O
Molecular Formula
C21H25BrN4O5
Molecular Weight
493.35
References & Citations
[1]Yang R, et al. Design, Synthesis, and Biological Evaluation of Selective TBL1X Degraders. ACS Med Chem Lett. 2024 Oct 1;15 (10) :1699-1707.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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