Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

XL-126

XL-126 (Compound 33) is a potent BD1-selective BET inhibitor, with a Kd of 8.9 nM. XL-126 leads to both the preservation of platelets and potent anti-inflammatory efficacy by BD1 selectivity[1].

Product Specifications

CAS Number

[3033576-12-1]

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/xl-126.html

Solubility

10 mM in DMSO

Smiles

O=C1C(NC2CCNCC2)=CC(C3=CC(NS(=O)(CC)=O)=C(C4=C3)C=CN4C(C)(C5=NC=CC=C5)C6=CC=CC=N6)=CN1C

Molecular Formula

C33H37N7O3S

Molecular Weight

611.76

References & Citations

[1]Li Y, et al. Structure-Guided Design and Synthesis of Pyridinone-Based Selective Bromodomain and Extra-Terminal Domain (BET) -First Bromodomain (BD1) Inhibitors. J Med Chem. 2024 Jan 31.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Dnajc5 (NM_024161) Rat Tagged Lenti ORF Clone
RR202869L3 10 µg

Dnajc5 (NM_024161) Rat Tagged Lenti ORF Clone

Ask
View Details
Pipemidic Acid hydrate
464557 50.0mg

Pipemidic Acid hydrate

Ask
View Details
Olfactory Receptor 52I2 (OR52I2) Antibody
abx026467-01 80 µL

Olfactory Receptor 52I2 (OR52I2) Antibody

Ask
View Details
Olfactory Receptor 52I2 (OR52I2) Antibody
abx026467-02 400 µL

Olfactory Receptor 52I2 (OR52I2) Antibody

Ask
View Details
Rabbit Polyclonal CDKAL1 Antibody [DyLight 550]
NBP2-98668R 0.1 mL

Rabbit Polyclonal CDKAL1 Antibody [DyLight 550]

Ask
View Details
Guinea pig 2, 4-dienoyl-CoA reductase, mitochondrial (DECR1) ELISA Kit
EIA07449Gu 1 Kit

Guinea pig 2, 4-dienoyl-CoA reductase, mitochondrial (DECR1) ELISA Kit

Ask
View Details