Cabazitaxel
Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.
Product Specifications
CAS Number
183133-96-2
Product Name Alternative
XRP6258; RPR-116258A; taxoid XRP6258
UNSPSC
12352005
Hazard Statement
H302, H315, H341, H361, H373
Target
Autophagy; Microtubule/Tubulin
Type
Natural Products
Related Pathways
Autophagy; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Cabazitaxel.html
Purity
99.98
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CC1=C([C@@H](OC)C([C@@]2(C)[C@@]3([H])[C@](OC(C)=O)(CO4)[C@H]4C[C@@H]2OC)=O)C(C)(C)[C@@]([C@H]3OC(C5=CC=CC=C5)=O)(O)C[C@@H]1OC([C@H](O)[C@H](C6=CC=CC=C6)NC(OC(C)(C)C)=O)=O
Molecular Formula
C45H57NO14
Molecular Weight
835.93
Precautions
H302, H315, H341, H361, H373
References & Citations
[1]Tai X, et al. Cabazitaxel and indocyanine green co-delivery tumor-targeting nanoparticle for improved antitumor efficacy and minimized drug toxicity. J Drug Target. 2016 Sep 9:1-29.|[2]Gdowski AS, et al. Bone-targeted cabazitaxel nanoparticles for metastatic prostate cancer skeletal lesions and pain. Nanomedicine (Lond) . 2017 Sep;12 (17) :2083-2095.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K1651903 1.0 µg DNA
PIN4 sgRNA CRISPR Lentivector (Human) (Target 2)
Sign In for Pricing
View Details NBP3-26099JF585 0.1 mL
Mouse Monoclonal GPRC5D Antibody (10) [Janelia Fluor 585]
Sign In for Pricing
View Details 
NBP2-97730MFV610 0.1 mL
Rabbit Polyclonal GPR180 Antibody [mFluor Violet 610 SE]
Sign In for Pricing
View Details