BGC-20-1531
BGC-20-1531 (PGN 1531), a benzenesulfonamide derivative, is a selective EP4 antagonist. BGC-20-1531 binds to PGE2 enhancing the ATPase activity, which are coupled to Gs proteins and thus activate adenylate cyclase generating cAMP and activating PKA. BGC-20-1531 is promising for research of liver disorders[1][2].
Product Specifications
CAS Number
1186532-61-5
Product Name Alternative
PGN 1531
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PKA; Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Stem Cell/Wnt; TGF-beta/Smad
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bgc-20-1531.html
Smiles
O=C(C1=CC(COC2=CC=C(C3=NC=C(C=C3)OC)C=C2)=C(C)O1)N([Na])S(=O)(C4=C(C)C=CC=C4)=O
Molecular Formula
C26H23N2NaO6S
Molecular Weight
514.53
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
EP
Frequently Asked Questions
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