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Protease-Activated Receptor-1, PAR-1 Agonist (TFA)

Protease-Activated Receptor-1, PAR-1 Agonist TFA is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist TFA corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor[1][2].

Product Specifications

UNSPSC

12352209

Target

Protease Activated Receptor (PAR)

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protease-activated-receptor-1-par-1-agonist-tfa.html

Purity

98.54

Solubility

H2O : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C([C@@H](N)[C@@H](C)O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC(N)=O)=O)CCCNC(N)=N)=O)CC(C)C)=O)CC(C)C)=O)CC1=CC=CC=C1.OC(C(F)(F)F)=O

Molecular Formula

C37H59F3N10O11

Molecular Weight

876.92

References & Citations

[1]Heider I, et al. PAR1-type thrombin receptor stimulates migration and matrix adhesion of human colon carcinoma cells by a PKCepsilon-dependent mechanism. Oncol Res. 2004;14 (10) :475-482.|[2]Stefanie Gödecke, et al. Thrombin-induced ATP release from human umbilical vein endothelial cells. Am J Physiol Cell Physiol. 2012 Mar 15;302 (6) :C915-23.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

PAR1

Available Sizes

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