Probimane
Probimane (AT-2153) is a potent anticancer agent. Probimane is effective against mouse tumors S37, S180, Lewis lung carcinoma, L1210 and human pulmonary adenocarcinoma heterotransplanted into nude mice[1].
Product Specifications
CAS Number
[108093-90-9]
Product Name Alternative
AT-2153
UNSPSC
12352005
Target
Calmodulin
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/probimane.html
Purity
99.91
Solubility
10 mM in DMSO
Smiles
O=C1N(CN2CCOCC2)C(CN(CC(C)N3CC(N(CN4CCOCC4)C(C3)=O)=O)C1)=O
Molecular Formula
C21H34N6O6
Molecular Weight
466.53
References & Citations
[1]Lu DY, et al. [Distribution of 14C labeled at dioxopiperazine or methyl morpholine group of probimane by whole body autoradiography]. Zhongguo Yao Li Xue Bao. 1993 Mar;14 (2) :171-3. Chinese.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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