OG-L002 (hydrochloride)
OG-L002 hydrochloride is a potent and highly selective LSD1 inhibitor with an IC50 of 0.02 μM. OG-L002 hydrochloride is a potent monoamine oxidases (MAO) inhibitor with IC50s of 1.38 μM and 0.72 μM for MAO-A and MAO-B, respectively. OG-L002 hydrochloride potently inhibits the expression of HSV IE genes[1].
Product Specifications
CAS Number
1357299-45-6
UNSPSC
12352005
Target
Histone Demethylase; HSV; Monoamine Oxidase
Type
Reference compound
Related Pathways
Anti-infection; Epigenetics; Neuronal Signaling
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/og-l002-hydrochloride.html
Smiles
OC1=CC(C2=CC=C([C@@H]3[C@@H](N)C3)C=C2)=CC=C1.[H]Cl
Molecular Formula
C15H16ClNO
Molecular Weight
261.75
References & Citations
[1]Liang Y, et al. A novel selective LSD1/KDM1A inhibitor epigenetically blocks herpes simplex virus lytic replication and reactivation from latency. mBio. 2013 Feb 5;4 (1) :e00558-12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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