Arformoterol (tartrate)

Arformoterol ((R, R) -Formoterol) tartrate, the (R, R) -enantiomer of Formoterol, is a long-acting β2-adrenergic receptor (β2-AR) agonist, with a Kd of 2.9 nM. Arformoterol tartrate can be used for the research of chronic obstructive pulmonary disease (COPD) [1][2].

Product Specifications

CAS Number

[200815-49-2]

Product Name Alternative

(R, R) -Formoterol (tartrate)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/arformoterol-tartrate.html

Purity

99.63

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic)

Smiles

OC1=CC=C([C@@H](O)CN[C@H](C)CC2=CC=C(OC)C=C2)C=C1NC=O.O=C(O)[C@H](O)[C@@H](O)C(O)=O

Molecular Formula

C23H30N2O10

Molecular Weight

494.49

Precautions

H302, H315, H319, H335

References & Citations

[1]Handley DA, et, al. Biological actions of formoterol isomers. Pulm Pharmacol Ther. 2002;15 (2) :135-45.|[2]Cazzola M, et, al. Arformoterol tartrate in the treatment of COPD. Expert Rev Respir Med. 2010 Apr;4 (2) :155-62.|[3]Song W, et, al. Postexposure administration of a {beta}2-agonist decreases chlorine-induced airway hyperreactivity in mice. Am J Respir Cell Mol Biol. 2011 Jul;45 (1) :88-94.