MMA-NODAGA

MMA-NODAGA is a chelator for site-specific labeling of targeting proteins containing unpaired cysteine. MMA-NODAGA can be used to conjugate with exosome and 64Cu in image with positron emission tomography (PET) [1].

Product Specifications

CAS Number

[1440903-11-6]

UNSPSC

12352005

Target

Radionuclide-Drug Conjugates (RDCs)

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mma-nodaga.html

Purity

91.02

Solubility

10 mM in DMSO

Smiles

O=C(CN1CCN(CCN(C(CCC(NCCN2C(C=CC2=O)=O)=O)C(O)=O)CC1)CC(O)=O)O

Molecular Formula

C21H31N5O9

Molecular Weight

497.50

References & Citations

[1]Sara F F Almeida , et al. Osteosarcoma-Derived Exosomes as Potential PET Imaging Nanocarriers for Lung Metastasis. Small. 2022 Dec;18 (49) :e2203999. |[2]Mohamed Altai, et al. Influence of nuclides and chelators on imaging using affibody molecules: comparative evaluation of recombinant affibody molecules site-specifically labeled with ⁶⁸Ga and ¹¹¹In via maleimido derivatives of DOTA and NODAGA. Bioconjug Chem. 2013 Jun 19;24 (6) :1102-9.