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Thymidine 3',5'-disphosphate

Product Specifications

Product Name Alternative

TNF Protease Inhibitor 2

UNSPSC Description

Thymidine 3',5'-disphosphate (Deoxythymidine 3′,5′-diphosphate; pdTp) is a selective small molecule inhibitor of staphylococcal nuclease and tudor domain containing 1 (SND1, the miRNA regulatory complex RISC subunit) and inhibits SND1 activity. Thymidine 3',5'-disphosphate exhibits anti-tumor efficacy in vivo[1].

Target Antigen

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/thymidine-3-5-disphosphate.html

Solubility

10 mM in DMSO

Smiles

OP(O)(O[C@H]1C[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1COP(O)(O)=O)=O

Molecular Weight

402.19

References & Citations

[1]Nidhi Jariwala, et al. Oncogenic Role of SND1 in Development and Progression of Hepatocellular Carcinoma. Cancer Res. 2017 Jun 15;77(12):3306-3316.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-115581/Thymidine-3-5-disphosphate-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-115581/

Clinical Information

No Development Reported

CAS Number

2863-04-9

Available Sizes

Curated Selection

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