Thymidine 3',5'-disphosphate
Thymidine 3',5'-disphosphate (Deoxythymidine 3′,5′-diphosphate; pdTp) is a selective small molecule inhibitor of staphylococcal nuclease and tudor domain containing 1 (SND1, the miRNA regulatory complex RISC subunit) and inhibits SND1 activity. Thymidine 3',5'-disphosphate exhibits anti-tumor efficacy in vivo[1].
Product Specifications
CAS Number
2863-04-9
Product Name Alternative
Deoxythymidine 3′,5′-diphosphate; pdTp
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thymidine-3-5-disphosphate.html
Solubility
10 mM in DMSO
Smiles
OP(O)(O[C@H]1C[C@H](N2C(NC(C(C)=C2)=O)=O)O[C@@H]1COP(O)(O)=O)=O
Molecular Formula
C10H16N2O11P2
Molecular Weight
402.19
References & Citations
[1]Nidhi Jariwala, et al. Oncogenic Role of SND1 in Development and Progression of Hepatocellular Carcinoma. Cancer Res. 2017 Jun 15;77 (12) :3306-3316.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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