RORγ inverse agonist 1
RORγ inverse agonist 1 is the inverse agonist of RORγ[1].
Product Specifications
CAS Number
529500-72-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
ROR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rorγ-inverse-agonist-1.html
Purity
99.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NCC1=CC=NC=C1)CN(S(=O)(C2=CC=C(C)C=C2)=O)C3=CC=CC(C(F)(F)F)=C3
Molecular Formula
C22H20F3N3O3S
Molecular Weight
463.47
Precautions
H302, H315, H319
References & Citations
[1]Song Y, et al. Identification of N-phenyl-2- (N-phenylphenylsulfonamido) acetamides as new RORγ inverse agonists: Virtual screening, structure-based optimization, and biological evaluation. Eur J Med Chem. 2016 Jun 30;116:13-26.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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