TDI-6570
Product Specifications
UNSPSC Description
TDI-6570 is a Cyclic GMP-AMP Synthase (cGAS) inhibitor with the IC50 of 0.138 μM[1].
Target Antigen
Cyclic GMP-AMP Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tdi-6570.html
Solubility
DMSO : 3.33 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(CO)N1CC2=C(CC1)N(C)C3=C2C=CC(Cl)=C3F
Molecular Weight
296.72
References & Citations
[1]Daisuke Tomita, et al. Inhibitors of cgas for treating autoinflammatory diseases and cancer metastasis. WO2020186027A1. 2020-09-17.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-164288/TDI-6570-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-164288/TDI-6570-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2287331-29-5
Available Sizes
Curated Selection
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