TDI-6570
TDI-6570 is a Cyclic GMP-AMP Synthase (cGAS) inhibitor with the IC50 of 0.138 μM[1].
Product Specifications
CAS Number
[2287331-29-5]
Product Name Alternative
TDI-006570
UNSPSC
12352005
Target
Cyclic GMP-AMP Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tdi-6570.html
Purity
99.64
Solubility
DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(CO)N1CC2=C(CC1)N(C)C3=C2C=CC(Cl)=C3F
Molecular Formula
C14H14ClFN2O2
Molecular Weight
296.72
References & Citations
[1]Daisuke Tomita, et al. Inhibitors of cgas for treating autoinflammatory diseases and cancer metastasis. WO2020186027A1. 2020-09-17.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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