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TDI-6570

TDI-6570 is a Cyclic GMP-AMP Synthase (cGAS) inhibitor with the IC50 of 0.138 μM[1].

Product Specifications

CAS Number

2287331-29-5

Product Name Alternative

TDI-006570

UNSPSC

12352005

Target

Cyclic GMP-AMP Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tdi-6570.html

Purity

99.64

Solubility

DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(CO)N1CC2=C(CC1)N(C)C3=C2C=CC(Cl)=C3F

Molecular Formula

C14H14ClFN2O2

Molecular Weight

296.72

References & Citations

[1]Daisuke Tomita, et al. Inhibitors of cgas for treating autoinflammatory diseases and cancer metastasis. WO2020186027A1. 2020-09-17.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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