Phosphorylcholine

Phosphatidylcholine is the main phospholipid component in eukaryotic biofilms. Phosphatidylcholine exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine exhibits a surprising range of immunomodulatory properties[1].

Product Specifications

CAS Number

[3616-04-4]

Product Name Alternative

Phosphocholine

UNSPSC

12352211

Target

Adrenergic Receptor; Endogenous Metabolite

Type

Natural Products

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Field of Research

Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/phosphorylcholine-1.html

Purity

98.0

Solubility

DMSO : < 1 mg/mL|Ethanol : 4 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=P(OCC[N+](C)(C)C)([O-])O

Molecular Formula

C5H14NO4P

Molecular Weight

183.14

References & Citations

[1]Harnett W, et al. Phosphorylcholine: friend or foe of the immune system? Immunol Today. 1999 Mar;20 (3) :125-9.|[2]Tu S, et al., Enhancement of cellular uptake and antitumor efficiencies of micelles with phosphorylcholine. Macromol Biosci. 2011 Oct 10;11 (10) :1416-25.|[3]Cansev M, et al., Choline, CDP-choline or phosphocholine increases plasma glucagon in rats: involvement of the peripheral autonomic nervous system. Eur J Pharmacol. 2008 Jul 28;589 (1-3) :315-22.|[4]Caligiuri G, et al., Phosphorylcholine-targeting immunization reduces atherosclerosis. J Am Coll Cardiol. 2007 Aug 7;50 (6) :540-6.