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12-O-Methylcarnosic acid

12-O-Methylcarnosic acid (12-Methoxycarnosic acid), a diterpene carnosic acid isolated from the acetone extract of Salvia microphylla, is an active constituent of 5α-reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid inhibits proliferation in LNCaP cells. 12-O-Methylcarnosic acid has antioxidant, anti-cancer and antimicrobial activity[1][2].

Product Specifications

CAS Number

[62201-71-2]

Product Name Alternative

12-Methoxycarnosic acid

UNSPSC

12352005

Hazard Statement

H302, H410

Target

5 alpha Reductase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/12-o-methylcarnosic-acid.html

Purity

99.67

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C([C@]12CCCC(C)(C)[C@]1([H])CCC3=C2C(O)=C(OC)C(C(C)C)=C3)O

Molecular Formula

C21H30O4

Molecular Weight

346.46

Precautions

H302, H410

References & Citations

[1]Kazuya Murata, et al. Promotion of Hair Growth by Rosmarinus Officinalis Leaf Extract. Phytother Res. 2013 Feb;27 (2) :212-7.|[2]Zeynep Aydogmuş, et al. Constituents of Salvia Microphylla. Nat Prod Res. 2006 Jul 10;20 (8) :775-81.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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