Biotinylated Cynomolgus KLRG1 Protein, Avitag™, His Tag
The co-inhibitory receptor killer-cell lectin like receptor G1 (KLRG1) is specifically expressed on NK cells and activated CD8+ T-cells and has been postulated to be a marker of senescence. KLRG1+ T cells are a major reason of chronic tissue damage in some autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. In tumors, tumor cells which express E-cadherin or N-cadherin bind to KLRG1 and inhibit the antitumor activity of T and NK cells. Thus, KLRG1 acts as an immunocheckpoint inhibitory receptor.
Product Specifications
Background
Specifications
Accession Number
A0A2K5WAP9
Expression Region
Leu 60 - Pro 189
Host
HEK293
Target
KLRG1
Conjugation
Biotin-labeled
Tag
N-Avi & N-10xHis
Source
Cynomolgus
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
18.5 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
25ug*1
Host or Source
HEK293
Species
Cynomolgus
Protein ID
A0A2K5WAP9
Preservative
Trehalose
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