MitoTracker Deep Red FM

MitoTracker Deep Red (MTDR) FM fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Deep Red FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 644/665 nm[1]. MitoTracker Deep Red dyes have an excitation/emission wavelength of 633/650-750 nm[2].The Ex/Em of MitoTracker Deep Red (MTDR) FM is 644/665 nm.

Product Specifications

CAS Number

[873315-86-7]

Product Name Alternative

MTDR FM

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mitotracker-deep-red-fm.html

Purity

99.0

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

ClCC1=CC=C(CN2C3=C(C(C)(C)/C2=C/C=C/C=C/C4=[N+](C)C5=C(C4(C)C)C=CC=C5)C=CC=C3)C=C1.[Cl-]

Molecular Formula

C34H36Cl2N2

Molecular Weight

543.57

References & Citations

[1]Buckman JF, et al. MitoTracker labeling in primary neuronal and astrocytic cultures: influence of mitochondrial membrane potential and oxidants. J Neurosci Methods. 2001 Jan 15;104 (2) :165-76.|[2]Wang FX, et al. Mitochondria-Accumulating Rhenium (I) Tricarbonyl Complexes Induce Cell Death via Irreversible Oxidative Stress and Glutathione Metabolism Disturbance. ACS Appl Mater Interfaces. 2019 Apr 10;11 (14) :13123-13133.