L-Moses (dihydrochloride)
L-Moses (L-45) dihydrochloride is the first potent, selective, and cell-active p300/CBP-associated factor (PCAF) bromodomain (Brd) inhibitor with a Kd of 126 nM[1].
Product Specifications
CAS Number
2922480-38-2
Product Name Alternative
L-45 (dihydrochloride)
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/L-45_dihydrochloride.html
Purity
99.38
Solubility
DMSO : ≥ 100 mg/mL
Smiles
C[C@@H]([C@H](C1=CC=CC=C1)N(C)C)NC(C2=C3C=CC=C2)=NN4C3=NN=C4C.[H]Cl.[H]Cl
Molecular Formula
C21H26Cl2N6
Molecular Weight
433.38
References & Citations
[1]Moustakim M, et al. Discovery of a PCAF Bromodomain Chemical Probe. Angew Chem Int Ed Engl. 2017 Jan 16;56 (3) :827-831.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Brd
Available Sizes
Frequently Asked Questions
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