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L-Moses (dihydrochloride)

L-Moses (L-45) dihydrochloride is the first potent, selective, and cell-active p300/CBP-associated factor (PCAF) bromodomain (Brd) inhibitor with a Kd of 126 nM[1].

Product Specifications

CAS Number

2922480-38-2

Product Name Alternative

L-45 (dihydrochloride)

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/L-45_dihydrochloride.html

Purity

99.38

Solubility

DMSO : ≥ 100 mg/mL

Smiles

C[C@@H]([C@H](C1=CC=CC=C1)N(C)C)NC(C2=C3C=CC=C2)=NN4C3=NN=C4C.[H]Cl.[H]Cl

Molecular Formula

C21H26Cl2N6

Molecular Weight

433.38

References & Citations

[1]Moustakim M, et al. Discovery of a PCAF Bromodomain Chemical Probe. Angew Chem Int Ed Engl. 2017 Jan 16;56 (3) :827-831.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Brd

Available Sizes

Frequently Asked Questions

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