N1, N11-Diethylnorspermine (hydrobromide)

N1, N11-Diethylnorspermine hydrobromide is a potent anticancer agent. N1, N11-Diethylnorspermine hydrobromide is a spermine analog that activates polyamine catabolism. N1, N11-Diethylnorspermine hydrobromide induces the release of cytochrome c from mitochondria, resulting in activation of caspase 3. N1, N11-Diethylnorspermine hydrobromide kills glioblastoma multiforme (GBM) cells through induction of SSAT (spermidine/spermine N1-acetyltransferase) coupled with H2O2 production[1][2][3].