Mal-PEG8-Val-Ala-PABC
Mal-PEG8-Val-Ala-PABC is a cleavable Tesirine linker used in the synthesis of Tesirine, a agent-linker conjugate for ADC[1].
Product Specifications
Product Name Alternative
MP-PEG8-Val-Ala-PABC; MP-PEG8-VA-PABC
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-peg8-val-ala-pabc.html
Purity
99.06
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)C(C)C)=O)C)NC2=CC=C(C=C2)CO
Molecular Formula
C41H65N5O15
Molecular Weight
867.98
References & Citations
[1]Congreve, S., et al. Antibody drug conjugates (ADC) : Current status and mapping of ADC:s in clinical programs.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
SEPT3 (septin 3, MGC133218, SEP3, bK250D10.3) (MaxLight 750)
Lentiviral mouse Ankrd28 shRNA (UAS) - Lentiviral mouse Ankrd28 shRNA (UAS, RFP) plasmid
Mouse Monoclonal DC-SIGN/CD209 Antibody (C209/1781) [Alexa Fluor 647]