Tyrphostin AG 112
Product Specifications
UNSPSC Description
Tyrphostin AG 112 is an EGFR phosphorylation inhibitor[1].
Target Antigen
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tyrphostin-ag-112.html
Purity
98.55
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
N#C/C(C#N)=C(N)/C(C#N)=C/C1=CC=C(O)C=C1
Molecular Weight
236.23
References & Citations
[1]Rodrigo Franco, et al. Epidermal Growth Factor Receptor Is Activated by Hyposmolarity and Is an Early Signal Modulating Osmolyte Efflux Pathways in Swiss 3T3 Fibroblasts. Pflugers Arch. 2004 Mar;447(6):830-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112474/Tyrphostin-AG-112-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112474/Tyrphostin-AG-112-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
144978-82-5
Available Sizes
Curated Selection
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