Tyrphostin AG 112

Tyrphostin AG 112 is an EGFR phosphorylation inhibitor[1].

Product Specifications

CAS Number

[144978-82-5]

UNSPSC

12352005

Hazard Statement

H301-H311-H331

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tyrphostin-ag-112.html

Purity

98.55

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

N#C/C(C#N)=C(N)/C(C#N)=C/C1=CC=C(O)C=C1

Molecular Formula

C13H8N4O

Molecular Weight

236.23

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

References & Citations

[1]Rodrigo Franco, et al. Epidermal Growth Factor Receptor Is Activated by Hyposmolarity and Is an Early Signal Modulating Osmolyte Efflux Pathways in Swiss 3T3 Fibroblasts. Pflugers Arch. 2004 Mar;447 (6) :830-9.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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