Tyrphostin AG 112
Tyrphostin AG 112 is an EGFR phosphorylation inhibitor[1].
Product Specifications
CAS Number
[144978-82-5]
UNSPSC
12352005
Hazard Statement
H301-H311-H331
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tyrphostin-ag-112.html
Purity
98.55
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
N#C/C(C#N)=C(N)/C(C#N)=C/C1=CC=C(O)C=C1
Molecular Formula
C13H8N4O
Molecular Weight
236.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
References & Citations
[1]Rodrigo Franco, et al. Epidermal Growth Factor Receptor Is Activated by Hyposmolarity and Is an Early Signal Modulating Osmolyte Efflux Pathways in Swiss 3T3 Fibroblasts. Pflugers Arch. 2004 Mar;447 (6) :830-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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